Project : MFA011
Indication : Oncology
| Discovery | Lead Optimization | Preclinical Efficacy | IND-enabling |
|---|---|---|---|
MFA011 enables targeted delivery of IL-15 to tumor-associated immune cells, maximizing immune activation where it is needed most, by combining our proprietary anti-TIGIT antibody with an engineered IL-15 cytokine.
Project : MFA031
Indication : Autoimmune Diseases, Transplantation
| Discovery | Lead Optimization | Preclinical Efficacy | IND-enabling |
|---|---|---|---|
MFA031 is a first-in-class TIGIT agonist–IL-10 fusion therapeutic designed to restore immune balance through targeted immune regulation.
Project : MFA041
Indication : Autoimmune Diseases
| Discovery | Lead Optimization | Preclinical Efficacy | IND-enabling |
|---|---|---|---|
Platform: MediLink™
A Plug-and-Play Platform for Precision Immunology
| Discovery | Lead Optimization | Preclinical Efficacy | IND-enabling |
|---|---|---|---|
MediLink is our proprietary plug-and-play platform for the development of precision immune therapeutics. By seamlessly integrating target-specific antibodies with engineered cytokines, the platform enables the development of novel therapeutic modalities with programmable biological functions.
Platform: MediKine™
Proprietary Engineered Cytokines
| Discovery | Lead Optimization | Preclinical Efficacy | CMC development | IND-enabling | Phase I |
|---|---|---|---|---|---|
MediKine™ is MMB’s proprietary engineered cytokine platform designed to optimize cytokine activity, improve safety, and extend therapeutic durability. By precisely controlling the strength, duration, and quality of cytokine signaling, MediKine™ enables targeted immune modulation with an improved therapeutic window.
| Pipeline | Indication | Modality | Discovery | Lead Optimization | Preclinical Efficacy | IND-enabling |
|---|---|---|---|---|---|---|
| MediLink™ Programs | ||||||
| MFA011 | Cancer | Fusion Ab | ||||
| MFA031 | Autoimmune Diseases, Transplantation |
Fusion Ab | ||||
| MFA041 | Autoimmune Diseases | Fusion Ab | ||||
| Platforms | ||||||
| MediLink™ Platform |
Cancer, Autoimmune Diseases |
Fusion Ab | ||||
| MediKine™ Platform |
Cancer, AutoimmuneDiseases |
Fusion Ab | ||||